CRISPR Gene Knockout, Activation, and Inhibition Plasmid Libraries

MiaoLingPlasmid provides a wide range of CRISPR pooled plasmid libraries for gene knockout, gene activation, and gene inhibition studies. The available libraries cover human, mouse, and E. coli genomes, as well as a variety of pathway- and gene-focused applications.

If you are interested in any of the libraries below, please contact us for availability, specifications, and pricing.

1. Human Genome-Wide CRISPR Knockout Libraries

• Human Genome-Wide CRISPR Knockout Single-Plasmid Library A

• Human Genome-Wide CRISPR Knockout Single-Plasmid Library B

• Human Genome-Wide CRISPR Knockout Dual-Plasmid Library A

• Human Genome-Wide CRISPR Knockout Dual-Plasmid Library B

• Human Genome-Wide Lentiviral CRISPR gRNA Library Version 1

• Human Paired-guide RNA (pgRNA) Library for lncRNAs

• Human Epigenetic Gene Knockout Library

• Human CRISPR Metabolic Gene Knockout Library

• Human Kinase Domain-Focused CRISPR Knockout Library

• Human DNA-Binding Domain-Focused CRISPR Knockout Library

• RNA-Binding Protein Pooled CRISPR Knockout Library

• Human lncRNA Splicing-Targeting CRISPR Library

• Human SLC Knockout Library

• Human Ubiquitination-Related Protein CRISPR KO Library

2. Mouse Genome-Wide CRISPR Knockout Libraries

• Mouse Genome-Wide CRISPR Knockout Single-Plasmid Library A

• Mouse Genome-Wide CRISPR Knockout Single-Plasmid Library B

• Mouse Genome-Wide CRISPR Knockout Dual-Plasmid Library A

• Mouse Genome-Wide CRISPR Knockout Dual-Plasmid Library B

• Mouse Genome-Wide Lentiviral CRISPR gRNA Library Version 2

• Mouse Metabolic Gene Knockout Library

• Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

• Mouse SLC Knockout Library

3. CRISPR Activation Libraries

CRISPR activation (CRISPRa) libraries are designed to enable genome-wide or targeted gene activation using transcriptional activation systems such as SAM and P65-HSF.

Human CRISPR Activation Libraries

• Human CRISPR Activation Library (SAM-2 Plasmid System)

• Human CRISPR Activation Library (SAM-3 Plasmid System)

• Human CRISPR lncRNA Activation Pooled Library (SAM-3 Plasmid System)

• Human Membrane Protein Activation Library

• Human SLC Activation Library

• Human CRISPR Activation Pooled Library (P65-HSF)

Mouse CRISPR Activation Libraries

• Mouse CRISPR Activation Pooled Library (P65-HSF)

• Mouse Genome-Wide CRISPR Activation Library (SAM-3 Plasmid System)

4. CRISPR Inhibition Libraries

CRISPR interference (CRISPRi) libraries are designed for gene repression without introducing permanent DNA sequence changes, making them useful for functional screening and gene regulation studies.

• Human CRISPR Inhibition Pooled Library

• Mouse CRISPR Inhibition Pooled Library

• Human CRISPRi Non-Coding Gene Libraries

• E. coli Genome-Wide CRISPRi Library

5. Focused CRISPR Libraries

In addition to genome-wide screening libraries, MiaoLingPlasmid provides focused CRISPR libraries targeting specific gene families, functional domains, biological pathways, and cellular processes.

These include libraries targeting:

• Metabolic genes

• Kinase domains

• DNA-binding domains

• RNA-binding proteins

• lncRNAs

• lncRNA splicing sites

• Solute carrier (SLC) genes

• Ubiquitination-related proteins

• Membrane proteins

• Cardiac transcriptional regulators

6. CRISPR Library Applications

These CRISPR libraries can be used for a wide range of functional genomics applications, including:

• Genome-wide gene knockout screening

• Targeted gene knockout screening

• Genome-wide gene activation screening

• CRISPR interference (CRISPRi) screening

• Functional genomics studies

• Gene function discovery

• Signaling pathway studies

• Metabolic pathway screening

• Drug target discovery

• Disease mechanism research

• Non-coding RNA functional studies

• Gene regulatory network analysis

7. Contact Us

MiaoLingPlasmid can provide a variety of CRISPR knockout, activation, and inhibition pooled libraries for different experimental requirements.

If you are looking for a specific genome-wide library, focused library, or custom CRISPR screening library, please contact us with your target species, screening strategy, and experimental requirements.

We can help you select a suitable CRISPR library based on your research needs.